Bovine coronavirus

Bovine coronavirus structural proteins.

The tissue culture-adapted strain (Mebus) of bovine coronavirus was grown in the presence of isotopically labeled amino acids, glucosamine, or orthophosphate for the purpose of analyzing the virion structural proteins. Five species of polypeptides were identified when purified virions were solubilized in urea and sodium dodecyl sulfate and resolved by polyacrylamide gel electrophoresis. Four sp...

Antigenic relationships among proteins of bovine coronavirus, human respiratory coronavirus OC43, and mouse hepatitis coronavirus A59.

Antisera prepared against each of three single and one pair of major structural proteins of the bovine coronavirus (Mebus strain) were used in immunoblotting studies to measure cross-reactivity with the structural proteins of the human coronavirus OC43 and the mouse hepatitis coronavirus A59. We conclude that the bovine coronavirus is comprised of four major structural proteins, gp190 (normally...

A Serological Comparison of Bovine Coronavirus Isolates

viii Chapter 1: Introduction 1 Chapter 2: Materials and Methods 63 Chapter 3: Isolation and Growth of Bovine 113 Coronaviruses Chapter 4: Monoclonal Antibodies to Bovine 133 Coronavirus Chapter 5: Structural Proteins of Bovine 172 Coronavirus Chapter 6: Strain Comparison of Bovine Coronaviruses 212 Chapter 7: Animal Models of Bovine Coronavirus 259 Infection Chapter 8: General Discussion 285 Ap...

Coronavirus in Gnotobiotic Calves Coronavirus and a Virulent Bovine Enteric Cross-Protection against a Human Enteric

Antibody response to equine coronavirus in horses inoculated with a bovine coronavirus vaccine

A vaccine for equine coronavirus (ECoV) is so far unavailable. Bovine coronavirus (BCoV) is antigenically related to ECoV; it is therefore possible that BCoV vaccine will induce antibodies against ECoV in horses. This study investigated antibody response to ECoV in horses inoculated with BCoV vaccine. Virus neutralization tests showed that antibody titers against ECoV increased in all six horse...